| Effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy. | |
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MedLine Citation:
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PMID: 16097060 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To determine the effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy. METHODS: Consecutive patients who underwent capsule endoscopy during the 16-mo study period were either given 250 mg oral erythromycin, 1 h prior to swallowing the capsule endoscope or nothing. The gastric and small bowel transit time, and the small bowel image quality were compared. RESULTS: Twenty-four patients received oral erythromycin whereas 14 patients were not given any prokinetic agent. Patients who received erythromycin had a significantly lower gastric transit time than control (16 min vs 70 min, P = 0.005), whereas the small bowel transit time was comparable between the two groups (227 min vs 183 min, P = 0.18). Incomplete small bowel examination was found in three patients of the control group and in one patient of the erythromycin group. There was no significant difference in the overall quality of small bowel images between the two groups. A marked reduction in gastric transit time was noted in two patients who had repeat capsule endoscopy after oral erythromycin. CONCLUSION: Use of oral erythromycin significantly reduces the gastric transit time of capsule endoscopy. |
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Authors:
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Wai K Leung; Francis K L Chan; Sara S L Fung; Mei-Yin Wong; Joseph J Y Sung |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 11 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-12 Completed Date: 2005-10-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4865-8 Citation Subset: IM |
Affiliation:
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Department of Medicine and Therapeutics, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China. wkleung@cuhk.edu.hk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Body Mass Index Capsules Endoscopy, Gastrointestinal / methods* Erythromycin / pharmacology* Female Gastrointestinal Transit / drug effects, physiology* Humans Intestine, Small / drug effects, physiology Kinetics Male Middle Aged Stomach / drug effects, physiology |
| Chemical | |
Reg. No./Substance:
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0/Capsules; 114-07-8/Erythromycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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