| Effect of omega-3 fatty acids on intensity of primary dysmenorrhea. | |
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MedLine Citation:
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PMID: 22261128 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To examine whether dietary supplementation with omega-3 fatty acids relieved symptoms of primary dysmenorrhea. METHODS: Women aged 18-22years with primary dysmenorrhea were enrolled in a double-blind crossover study. Women assigned to group 1 (n=47) received 1 omega-3 capsule daily for 3months, followed by placebo for 3months. Women in group 2 (n=48) received placebo for 3months, followed by omega-3 for 3months. A washout period was performed in both groups. Participants used 400mg of ibuprofen as a rescue dose if severe menstrual pains were experienced. RESULTS: A marked reduction in pain intensity was observed after 3months of treatment with omega-3 fatty acids (P<0.05). Women who received omega-3 fatty acids required fewer rescue doses than women who received placebo (P<0.05). The mean numbers of ibuprofen tablets used after 3months with omega-3 fatty acids were 4.3±2.1 (group 1) and 3.2±2.5 (group 2); the mean numbers of tablets used after 3months of placebo were 5.3±2.2 (group 1) and 6.0±2.6 (group 2) (P=0.001 for both). CONCLUSION: Supplementation with omega-3 fatty acids reduced the symptom intensity of primary dysmenorrhea. Supplementation efficacy was sufficient to decrease the ibuprofen rescue dose. |
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Authors:
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Nahid Rahbar; Neda Asgharzadeh; Raheb Ghorbani |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-17 |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: - ISSN: 1879-3479 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Obstetrics and Gynecology, Amir-al-Momenin Hospital, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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