Document Detail

Effect of olive pomace extracts on hyperlipidaemia.
MedLine Citation:
PMID:  21740285     Owner:  NLM     Status:  In-Data-Review    
In this study, we have examined the hypolipidemic effect of olive pomace extracts. Identification and quantitation of maslinic acid and oleanolic acid as the potentially effective components of the pomace extracts were carried out by high performance liquid chromatography methods. Hyperlipidaemia was induced in male Sprague Dawley rats by feeding them with a high cholesterol diet for 30 days. The olive pomace extracts were supplemented (200?mg?kg(?1)?body wt?day(?1)) for 15 days. The levels of serum total cholesterol, triglyceride, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, aspartate aminotransferase and alanine aminotransferase increased in rats with hyperlipidaemia. Treatment with the olive pomace extracts significantly modulated the abnormalities induced by hyperlipidaemia. Lipid accumulation was decreased in histological findings. This study provides the possibility of utilising the olive pomaces for the prevention and treatment of hyperlipidaemia.
Jun Liu; Hongbin Sun; Jing Shang; Yuanyuan Yong; Luyong Zhang
Related Documents :
24396255 - Erythropoietin has a restorative effect on the contractility of arteries following expe...
23685825 - Reductions in serum lipids with a 4-year decline in serum perfluorooctanoic acid and pe...
24329875 - Cholesterol as a causative factor in alzheimer disease: a debatable hypothesis.
7956575 - Methods to prevent colonic injury in pelvic radiation.
7620885 - Reductions in body weight following chronic central opioid receptor subtype antagonists...
3661475 - Physical activity and plasma total- and hdl-cholesterol levels in western samoan men.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Natural product research     Volume:  25     ISSN:  1478-6427     ISO Abbreviation:  Nat. Prod. Res.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1190-4     Citation Subset:  IM    
a National Drug Screening Center, China Pharmaceutical University , 24 Tongjiaxiang , Nanjing 210009 , China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea.
Next Document:  Evaluation of antileishmanial, cytotoxic and antioxidant activities of essential oils extracted from...