Document Detail


Effect of oleanane triterpenoids from Terminalia arjuna--a cardioprotective drug on the process of respiratory oxyburst.
MedLine Citation:
PMID:  15957375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The oleanane triterpenes arjunic acid, arjungenin and their glucosides, arjunetin and arjunglucoside II, were isolated from the bark of Terminalia arjuna. Arjungenin and its glucoside exhibited a moderate free radical scavenging activity while all the compounds showed no effect on the superoxide release from PMN cells. Further arjungenin also exhibited greater inhibitory action on the hypochlorous acid production from human neutrophils.
Authors:
R S Pawar; K K Bhutani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Phytomedicine : international journal of phytotherapy and phytopharmacology     Volume:  12     ISSN:  0944-7113     ISO Abbreviation:  Phytomedicine     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-06-16     Completed Date:  2005-07-21     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9438794     Medline TA:  Phytomedicine     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  391-3     Citation Subset:  IM    
Affiliation:
Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sect. 67, S.A.S. Nagar, Phase X, (Mohali), Punjab, India.
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MeSH Terms
Descriptor/Qualifier:
Biphenyl Compounds
Cardiotonic Agents / administration & dosage,  pharmacology*,  therapeutic use
Free Radical Scavengers / administration & dosage,  pharmacology*,  therapeutic use
Humans
Neutrophils / drug effects*
Phytotherapy*
Picrates / chemistry
Plant Bark
Plant Extracts / administration & dosage,  pharmacology*,  therapeutic use
Terminalia*
Triterpenes / administration & dosage,  pharmacology,  therapeutic use
Chemical
Reg. No./Substance:
0/Biphenyl Compounds; 0/Cardiotonic Agents; 0/Free Radical Scavengers; 0/Picrates; 0/Plant Extracts; 0/Triterpenes; 0/arjunic acid; 1898-66-4/2,2-diphenyl-1-picrylhydrazyl

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