Document Detail

Effect of oil containing n-3 polyunsaturated fatty acids (PUFA) on the immune response and growth factors in piglets.
MedLine Citation:
PMID:  10497826     Owner:  NLM     Status:  MEDLINE    
Oral administration of n-3 polyunsaturated fatty acids (PUFA) to piglets slightly enhances the immune response. As compared to the control, in the experimental piglets the absolute values of monocytes in the peripheral blood were significantly increased (P < 0.05), while the metabolic activity of phagocytes and the number of lymphocytes within the individual subpopulations were slightly higher. The level of growth factors, determined on the basis of somatomedin in the blood serum, was significantly higher in the experimental group (P < 0.05). n-3 PUFA interfere with the synthesis of prostaglandins and influence the metabolism of fatty acids. This finding may contribute to the therapy of inflammatory processes influencing immune and growth factors in piglets.
R Kastel; V Revajová; D Magic; J Pistl; M Levkut; L Bindas; J Sajbidor; M Horváth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta veterinaria Hungarica     Volume:  47     ISSN:  0236-6290     ISO Abbreviation:  Acta Vet. Hung.     Publication Date:  1999  
Date Detail:
Created Date:  1999-10-19     Completed Date:  1999-10-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8406376     Medline TA:  Acta Vet Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  325-34     Citation Subset:  IM    
University of Veterinary Medicine, Kosice, Slovak Republic.
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MeSH Terms
Dietary Fats / immunology,  pharmacology*
Fatty Acids, Omega-3 / administration & dosage,  immunology,  pharmacology*
Flow Cytometry
Growth Substances / blood*
Immunity, Cellular
Swine / growth & development*,  immunology*
Reg. No./Substance:
0/Dietary Fats; 0/Fatty Acids, Omega-3; 0/Growth Substances

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