Document Detail


Effect of ocular perfusion pressure on retinal function in the rabbit.
MedLine Citation:
PMID:  9381670     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The electroretinogram (ERG) vs perfusion pressure relation was studied in anesthetized rabbits during mechanically induced changes in mean arterial pressure (MAP). After 1 hr of dark adaptation, ERGs were obtained at perfusion pressures from 10 to 95 mmHg with each pressure held for 30-60 sec, and at three levels from 15 to 75 mmHg with each pressure held for 5 min. The slopes of the b-wave amplitude vs perfusion pressure data were not significantly different from zero during either the brief or longer manipulations of perfusion pressure. However, the b-wave was nearly extinguished 5 min after death. The results indicate that the rabbit ERG is maintained over a wide range of perfusion pressure.
Authors:
J M Harrison; J W Kiel; S Smith
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Vision research     Volume:  37     ISSN:  0042-6989     ISO Abbreviation:  Vision Res.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-11-10     Completed Date:  1997-11-10     Revised Date:  2013-01-31    
Medline Journal Info:
Nlm Unique ID:  0417402     Medline TA:  Vision Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2339-47     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, University of Texas Health Science Center, San Antonio 78284, USA. harrisonj@uthscsa.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / physiology
Choroid / blood supply
Dark Adaptation / physiology
Electroretinography*
Eye / blood supply*
Intraocular Pressure / physiology
Rabbits
Regional Blood Flow
Retina / physiology
Grant Support
ID/Acronym/Agency:
EY09702/EY/NEI NIH HHS; R01 EY009702/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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