| Effect of ocular perfusion pressure on retinal function in the rabbit. | |
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MedLine Citation:
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PMID: 9381670 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The electroretinogram (ERG) vs perfusion pressure relation was studied in anesthetized rabbits during mechanically induced changes in mean arterial pressure (MAP). After 1 hr of dark adaptation, ERGs were obtained at perfusion pressures from 10 to 95 mmHg with each pressure held for 30-60 sec, and at three levels from 15 to 75 mmHg with each pressure held for 5 min. The slopes of the b-wave amplitude vs perfusion pressure data were not significantly different from zero during either the brief or longer manipulations of perfusion pressure. However, the b-wave was nearly extinguished 5 min after death. The results indicate that the rabbit ERG is maintained over a wide range of perfusion pressure. |
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Authors:
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J M Harrison; J W Kiel; S Smith |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Vision research Volume: 37 ISSN: 0042-6989 ISO Abbreviation: Vision Res. Publication Date: 1997 Sep |
Date Detail:
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Created Date: 1997-11-10 Completed Date: 1997-11-10 Revised Date: 2013-01-31 |
Medline Journal Info:
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Nlm Unique ID: 0417402 Medline TA: Vision Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 2339-47 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Texas Health Science Center, San Antonio 78284, USA. harrisonj@uthscsa.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology Choroid / blood supply Dark Adaptation / physiology Electroretinography* Eye / blood supply* Intraocular Pressure / physiology Rabbits Regional Blood Flow Retina / physiology |
| Grant Support | |
ID/Acronym/Agency:
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EY09702/EY/NEI NIH HHS; R01 EY009702/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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