Document Detail

Effect of nibbling and gorging dietary regimens on weight and lipid profile in rat.
MedLine Citation:
PMID:  19093509     Owner:  NLM     Status:  MEDLINE    
To investigate the effects of nibbling and gorging dietary regimens on weight and lipid profiles in rat, thirty female Wistar rats, after 10 day acclimatization period, were weighed and randomly assigned into two equal groups. They were fed the same food for 60 days as eight meals at 2 h intervals starting from 6 pm (nibbling group) or as two meals at 9 pm and 6 am (gorging group). The serum lipid levels and weight of animals were determined before and after the intervention. The body weight in two groups increased significantly (p < 0.001) during the period of study but there was no significant (p > 0.05) difference between two groups before and after the intervention. Nibbling regimen caused a reduction in the serum Total Cholesterol (TC), triglyceride and LDL-C levels, whereas these parameters increased during gorging diet. However, none of these changes were significant. There was a significant decrease (p < 0.05) in TC and LDL-C levels in nibbling diet compared to gorging one. According to obtained results, nibbling regimen has better effect on lipid profile than gorging one in rat.
M Shahraki; S Mahboob; M R Rashidi; M Majidi; M Mesgari; Z T Shahraki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pakistan journal of biological sciences: PJBS     Volume:  10     ISSN:  1028-8880     ISO Abbreviation:  Pak. J. Biol. Sci.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-12-19     Completed Date:  2009-02-25     Revised Date:  2009-03-13    
Medline Journal Info:
Nlm Unique ID:  101247723     Medline TA:  Pak J Biol Sci     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  4444-8     Citation Subset:  IM    
Department of Nutrition, Faculty of Medical, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.
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MeSH Terms
Animal Feed*
Body Weight / physiology*
Dietary Fats*
Feeding Behavior / physiology*
Lipids / analysis*
Rats, Wistar
Reg. No./Substance:
0/Dietary Fats; 0/Lipids

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