Document Detail


Effect of multivitamin supplements on weight gain during pregnancy among HIV-negative women in Tanzania.
MedLine Citation:
PMID:  23253638     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Multivitamin supplementation has been shown to reduce the risk of low birthweight. This effect could be mediated through gestational weight gain. However, the effect of multivitamin supplementation on weight gain during pregnancy has not been fully studied. The objective of this study was to examine the effects of multivitamins on pregnancy weight gain. We enrolled 8468 HIV-negative women from Dar es Salaam, Tanzania, in a randomised, placebo-controlled trial of multivitamins on birth outcomes. Women were randomly assigned to receive either a daily oral dose of multivitamin tablets or a placebo and were weighed every 4 weeks from enrolment until the last visit before delivery. Intent-to-treat analyses were carried out to examine the effects of multivitamins on pregnancy weight gain. Multivariate linear and binomial regression models with the log-link function were used to examine the association of weight gain during pregnancy to birthweight. The overall total weight gain was 253 g (SE: 69, P: 0.0003) more, while the overall 4 weekly weight gain was 59 g greater (SE: 18, P: 0.005) among women who received multivitamins compared to placebo. Women in the lowest quartile of gestational weight gain had babies with an average birthweight of 3030 g (SD: 524), while women in the highest quartile had babies weighing 3246 g (SD: 486), on average. Prenatal multivitamin supplements increased gestational weight gain, which was a significant predictor of birthweight.
Authors:
Freeman T Changamire; Ramadhani S Mwiru; Karen E Peterson; Gernard I Msamanga; Donna Spiegelman; Paul Petraro; Willy Urassa; Wafaie W Fawzi
Related Documents :
3777858 - Functional phospholipid/sphingomyelin ratio: an easy to interpret indicator of fetal lu...
7847558 - The t/qrs ratio of the electrocardiogram does not reliably reflect well-being in fetal ...
889728 - Correlation between thromboplastic activity and lecithin/sphingomyelin ratio in amnioti...
9819148 - Embryonic development of the ureter.
20416998 - 'high-risk' pregnancy after perinatal loss: understanding the label.
3131158 - Luteal function following ovarian stimulation in rhesus monkeys for in vitro fertilizat...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-17
Journal Detail:
Title:  Maternal & child nutrition     Volume:  -     ISSN:  1740-8709     ISO Abbreviation:  Matern Child Nutr     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101201025     Medline TA:  Matern Child Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Publishing Ltd.
Affiliation:
Department of Family Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Is there survival benefit from life-long follow-up after treatment for differentiated thyroid cancer...
Next Document:  Comparison of efficacy and satisfaction profile, between penile prosthesis implantation and oral PDE...