Document Detail

Effect of mitral valve replacement on left ventricular function in mitral regurgitation.
MedLine Citation:
PMID:  6830666     Owner:  NLM     Status:  MEDLINE    
To evaluate the effect of mitral valve replacement on left ventricular function in mitral regurgitation, we measured (1) the end-systolic stress/volume ratio, which is practically independent of changes in loading conditions, and (2) the left ventricular contractile reserves upon isometric exercise, both before and one year after mitral valve replacement in 11 patients with mitral regurgitation. The end-systolic stress/volume ratio increased, though the ejection fraction decreased after mitral valve replacement. The ejection fraction decreased and the end-systolic stress/volume ratio remained unchanged during isometric exercise before operation, whereas afterwards the ejection fraction remained unchanged and the end-systolic stress/volume ratio increased during exercise. Ventricular function improves after mitral valve replacement in patients with mitral regurgitation, though the ejection fraction, which is affected by altered loading conditions, deteriorates. The left ventricular response to stress caused by isometric exercise is also improved after surgery.
H V Huikuri
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British heart journal     Volume:  49     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  328-33     Citation Subset:  AIM; IM    
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MeSH Terms
Evaluation Studies as Topic
Heart Valve Prosthesis*
Heart Ventricles / physiopathology*
Isometric Contraction
Middle Aged
Mitral Valve / surgery
Mitral Valve Insufficiency / physiopathology*,  surgery
Myocardial Contraction
Postoperative Period
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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