| Effect of mirthful laughter on vascular function. | |
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MedLine Citation:
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PMID: 20816128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In contrast to the well-established scientific evidence linking negative emotional states (e.g., depression, anxiety, or anger) to increased risk for cardiovascular disease, much less is known about the association between positive emotional states (e.g., laughter, happiness) and cardiovascular health. We determined the effects of mirthful laughter, elicited by watching comic movies, on endothelial function and central artery compliance. Seventeen apparently healthy adults (23 to 42 years of age) watched 30 minutes of a comedy or a documentary (control) on separate days (crossover design). Heart rate and blood pressure increased significantly while watching the comedy, whereas no such changes were seen while watching the documentary. Ischemia-induced brachial artery flow-mediated vasodilation (by B-mode ultrasound imaging) increased significantly after watching the comedy (17%) and decreased with watching the documentary (-15%). Carotid arterial compliance (by simultaneous application of ultrasound imaging and applanation tonometry) increased (10%) significantly immediately after watching the comedy and returned to baseline 24 hours after the watching, whereas it did not change significantly throughout the documentary condition. Comedy-induced changes in arterial compliance were significantly associated with baseline flow-mediated dilation (r = 0.63). These results suggest that mirthful laughter elicited by comic movies induces beneficial impact on vascular function. |
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Authors:
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Jun Sugawara; Takashi Tarumi; Hirofumi Tanaka |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of cardiology Volume: 106 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-06 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 856-9 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan. jun.sugawara@aist.go.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Autonomic Nervous System / physiology Blood Pressure* Brachial Artery / physiology, ultrasonography Carotid Arteries / physiology, ultrasonography Case-Control Studies Compliance Diastole Endothelium, Vascular / physiology*, ultrasonography* Female Heart Rate* Humans Laughter* Male Reference Values Systole Vasodilation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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