Document Detail

Effect of mineral supplements to citric acid on enamel erosion.
MedLine Citation:
PMID:  14550377     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to evaluate the effect of mineral supplements to citric acid (1%; pH 2.21) on enamel erosion under controlled conditions in an artificial mouth. From each of 156 bovine incisors one polished enamel sample was prepared. The samples were divided among 13 experimental groups (n=12). In group 1 citric acid only was used (control). In groups 2-10 either calcium, phosphate or fluoride in various low concentrations was admixed to the citric acid. In groups 11-13 the citric acid was supplemented with a mixture of calcium, phosphate and fluoride. For demineralisation the specimens were rinsed with the respective solution for 1 min, immediately followed by a remineralisation period with artificial saliva (1 min). The specimens were cycled through this alternating procedure five times followed by rinsing for 8 h with artificial saliva. The de- and remineralisation cycle was repeated three times for each specimen interrupted by the 8 h-remineralisation periods. Before and after the experiments, the specimens were examined using microhardness testing (Knoop hardness) and laser profilometry. Hardness loss and enamel dissolution was significantly higher for the controls as compared to the remaining groups. Significantly lowest hardness loss for all groups was recorded for group 12 with admixture of calcium, phosphate and fluoride to citric acid. The significantly highest enamel loss was recorded for the controls compared to all other samples. Groups 3 and 4 revealed significantly lower and higher tissue loss compared to the remaining groups (2-13), respectively. The other groups did not differ significantly from each other. Modification of citric acid with calcium, phosphate and fluoride exerts a significant protective potential with respect to dental erosion. However, with the low concentrations applied enamel dissolution could not be completely prevented.
T Attin; K Meyer; E Hellwig; W Buchalla; A M Lennon
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of oral biology     Volume:  48     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-10-10     Completed Date:  2003-12-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  753-9     Citation Subset:  D; IM    
Department of Operative and Preventive Dentistry and Periodontology, Georg-August-University Göttingen, Robert-Koch-Str. 40, D-37075, Göttingen, Germany.
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MeSH Terms
Calcium / pharmacology
Citric Acid / antagonists & inhibitors*,  pharmacology
Dental Enamel Solubility / drug effects*
Fluorides / pharmacology
Hardness / drug effects
Hardness Tests / methods
Minerals / pharmacology*
Phosphates / pharmacology
Tooth Demineralization / chemically induced*
Reg. No./Substance:
0/Fluorides; 0/Minerals; 0/Phosphates; 7440-70-2/Calcium; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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