Document Detail

Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering.
MedLine Citation:
PMID:  3111305     Owner:  NLM     Status:  MEDLINE    
Meperidine has been used to suppress postanesthesia shivering. However, its efficacy to date has only been assessed by observation of visible shivering. We measured the effect of meperidine on oxygen consumption (VO2), carbon dioxide production (VCO2) and pulmonary gas exchange in 14 otherwise healthy patients shivering after general anesthesia. Meperidine successfully suppressed visible shivering in all patients and was associated with significant decreases in VO2, and VCO2 and minute ventilation (VE) but not with return to basal levels. Arterial PCO2 levels remained unchanged at normal, whereas significant improvements occurred in pH and bicarbonate levels. Meperidine is an effective method of reducing the elevated metabolic demand of shivering.
P E Macintyre; E G Pavlin; J F Dwersteg
Related Documents :
7462915 - The effects of chlorine dioxide and sodium chlorite on erythrocytes of a/j and c57l/j m...
17406905 - Effects of nutritional restriction on nitrogen and carbon stable isotopes in growing se...
15776255 - Distributions of c22-c30 even-carbon-number n-alkanes in ocean anoxic event 1 samples f...
17813375 - Carbon-13 depletion in a hydrothermal vent mussel: suggestion of a chemosynthetic food ...
10191535 - Value assignment of retinol, retinyl palmitate, tocopherol, and carotenoid concentratio...
10048795 - Description and evaluation of an experimental model to examine changes in selection bet...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  66     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1987 Aug 
Date Detail:
Created Date:  1987-08-24     Completed Date:  1987-08-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  751-5     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acidosis / drug therapy
Anesthesia, General / adverse effects*
Carbon Dioxide / metabolism*
Meperidine / pharmacology*,  therapeutic use
Oxygen Consumption / drug effects*
Pulmonary Gas Exchange / drug effects*
Shivering / drug effects*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 57-42-1/Meperidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ventilatory response to carbon dioxide after intramuscular and epidural fentanyl.
Next Document:  Prolonged hypocapnia does not alter the rate of CSF production in dogs during halothane anesthesia o...