Document Detail

Effect of menstrual cycle phase on carbohydrate supplementation during prolonged exercise to fatigue.
MedLine Citation:
PMID:  10658039     Owner:  NLM     Status:  MEDLINE    
The effects of menstrual cycle phase and carbohydrate (CHO) supplementation were investigated during prolonged exercise. Nine healthy, moderately trained women cycled at 70% peak O(2) consumption until exhaustion. Two trials were completed during the follicular (Fol) and luteal (Lut) phases of the menstrual cycle. Subjects consumed 0.6 g CHO. kg body wt(-1). h(-1) (5 ml/kg of a 6% CHO solution every 30 min beginning at min 30 of exercise) or a placebo drink (Pl) during exercise. Time to exhaustion during CHO increased from Pl values (P < 0.05) by 14.4 +/- 8.5 (Fol) and 11.4 +/- 7.1% (Lut); no differences were observed between menstrual cycle phases. CHO attenuated (P < 0.05) the decrease in plasma glucose and insulin and the increase in plasma free fatty acids, tryptophan, epinephrine, and cortisol observed during Pl for both phases. Plasma alanine, glutamine, proline, and isoleucine were lower (P < 0.05) in Lut than in Fol phase. CHO resulted in lower (P < 0.05) plasma tyrosine, valine, leucine, isoleucine, and phenylalanine. These results indicate that the menstrual cycle phase does not alter the effects of CHO supplementation on performance and plasma levels of related substrates during prolonged exercise.
S P Bailey; C M Zacher; K D Mittleman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  88     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-03     Completed Date:  2000-03-03     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  690-7     Citation Subset:  IM; S    
Department of Physical Therapy Education, Elon College, Elon College, North Carolina 27244, USA.
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MeSH Terms
Amino Acids / blood
Blood Pressure / drug effects
Dietary Carbohydrates / administration & dosage*
Dietary Supplements
Epinephrine / blood
Exercise / physiology*
Fatigue / physiopathology*,  psychology
Fatty Acids, Nonesterified / blood
Heart Rate / drug effects
Hydrocortisone / blood
Insulin / blood
Menstrual Cycle / physiology*
Norepinephrine / blood
Oxygen Consumption / drug effects,  physiology
Pulmonary Gas Exchange / drug effects
Reg. No./Substance:
0/Amino Acids; 0/Dietary Carbohydrates; 0/Fatty Acids, Nonesterified; 0/Insulin; 50-23-7/Hydrocortisone; 51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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