| Effect measures for behavioral factors adversely affecting fetal growth. | |
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MedLine Citation:
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PMID: 8672184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to estimate the proportion of ultrasonically diagnosed fetal growth retardation that may be attributable to potentially remediable factors (for example, cigarette smoking, alcohol use, and drug addition). We computed multivariate odds ratios for fetal growth retardation associated with cigarette smoking and alcohol and illicit drug consumption in 350 singleton pregnancies complicated by fetal growth retardation and 700 controls. The odds ratio of fetal growth retardation among women who smoked throughout pregnancy was 2.61 (95% confidence interval, 1.38 to 4.93) compared to women who claimed to have stopped smoking by the 18th week of gestation. The summary attributable risk of fetal growth retardation associated with behavioral variables measured during the first trimester and thereafter ranged from 18 to 21%. By implication, the maximum proportion of fetal growth retardation that could theoretically be prevented by eliminating these risk factors accounts for about 1% of all births. However, allowance for the limited modifiability of preventable factors and the consistent overlap between them would probably reduce such estimate to less than 1%. We conclude that only interventions to reduce the prevalence of strong risk factors (for example, preeclampsia, sociodemographic variables) may have a substantial effect on the incidence of impaired fetal growth and subsequent infant morbidity. |
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Authors:
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A Spinillo; E Capuzzo; G Piazzi; F Baltaro; A Iasci; S Nicola |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of perinatology Volume: 13 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-08-15 Completed Date: 1996-08-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 119-23 Citation Subset: IM |
Affiliation:
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Clinica Ostetrico-Ginecologica, IRCCS Policlinico San Matteo, Pavia, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Drinking / adverse effects*, epidemiology Case-Control Studies Female Fetal Growth Retardation / epidemiology, etiology*, ultrasonography Humans Odds Ratio Pregnancy Pregnancy Complications* / epidemiology Prevalence Risk Factors Smoking / adverse effects*, epidemiology Substance-Related Disorders / complications*, epidemiology Ultrasonography, Prenatal Weight Gain |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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