| Effect of measles-virus infection and interferon treatment on invasiveness of Shigella flexneri in HEp2-cell cultures. | |
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MedLine Citation:
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PMID: 3098977 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of measles-virus infection on the invasiveness of Shigella flexneri in HEp2-cell cultures was studied. Bacterial invasiveness was significantly enhanced in cell cultures incubated with virus before bacterial inoculation. This effect was a function of time after introduction of virus to the cell cultures and of the concentration of virus. The increase in bacterial invasiveness was observed before production of infectious virus particles and before a cytopathic effect was evident. A similar enhancement of invasiveness was demonstrated when cell cultures were pretreated with UV-inactivated measles virus. Pretreatment of cells with interferon did not influence invasiveness, although it reduced the effect of measles-virus infection. |
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Authors:
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G Bukholm; K Modalsli; M Degré |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of medical microbiology Volume: 22 ISSN: 0022-2615 ISO Abbreviation: J. Med. Microbiol. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-02-19 Completed Date: 1987-02-19 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0224131 Medline TA: J Med Microbiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 335-41 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Adhesion Cell Line Humans Interferon Type I / pharmacology* Interferon-gamma / pharmacology* Measles virus / physiology*, radiation effects Shigella flexneri / pathogenicity* Ultraviolet Rays |
| Chemical | |
Reg. No./Substance:
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0/Interferon Type I; 82115-62-6/Interferon-gamma |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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