| Effect of long-term spleen dialysate (Solcosplen) administration on plasma lipids and lipoproteins in early postmenopausal women. | |
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MedLine Citation:
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PMID: 8213229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 46 early postmenopausal women with elevated levels of total cholesterol, triglycerides, low-density lipid (LDL) cholesterol and lowered high density lipoprotein cholesterol (HDL) cholesterol was treated with spleen dialysate (Solcosplen), 2 x 2 tablets daily for 6 months. Serum estradiol levels rose from 42.3 +/- 15.4 pg/ml to 60.6 +/- 23.6 pg/ml and the Kupperman Index decreased significantly after 6 months of treatment. Also, a significant decrease of total cholesterol, triglycerides, LDL cholesterol, and an increase of HDL cholesterol was observed. The changes showed no correlation with the estradiol concentration and no side-effects were evident. Solcosplen is recommended as a beneficial therapy for women in the early postmenopause. |
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Authors:
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A Milewicz; T Teucher; H Schmitz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Volume: 7 ISSN: 0951-3590 ISO Abbreviation: Gynecol. Endocrinol. Publication Date: 1993 Jun |
Date Detail:
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Created Date: 1993-11-01 Completed Date: 1993-11-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8807913 Medline TA: Gynecol Endocrinol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 143-7 Citation Subset: IM |
Affiliation:
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Department of Endocrinology, Medical Academy, Wroclaw, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticholesteremic Agents
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pharmacology* Estradiol / blood Female Follicle Stimulating Hormone / blood Humans Lipids / blood* Lipoproteins / blood* Longitudinal Studies Luteinizing Hormone / blood Middle Aged Postmenopause / metabolism* Progesterone / blood Prolactin / blood Spleen / physiology* Testosterone / blood Time Factors Tissue Extracts / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Anticholesteremic Agents; 0/Lipids; 0/Lipoproteins; 0/Solcosplen; 0/Tissue Extracts; 50-28-2/Estradiol; 57-83-0/Progesterone; 58-22-0/Testosterone; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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