| Effect of long term low-fat dietary intervention on change in hemostatic factors: Results from the Women's Health Initiative. | |
| | |
MedLine Citation:
|
PMID: 20884191 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Low-fat diet may play a role in prevention of cardiovascular disease (CVD) by altering the levels of hemostatic factors. There are yet limited data on the effects of low-fat diet on the circulating levels of these factors and existing studies are limited by small sample size and short duration of follow-up. We conducted an analysis in a subset of women (active arm = 723; control arm = 1036) within the Women's Health Initiative Dietary Modification Trial to investigate the long term effect of a low-fat diet on circulating levels of fibrinogen, factor VII concentration and factor VII activity among postmenopausal women aged 50-79 years. Using linear mixed effects model with random intercept and data from three follow-up visits (years 1, 3 and 6) we evaluated the change in each factor over time. Overall, the changes in these factors were small (less than 5%) in both the arms of the trials at the end of intervention and there was no significant difference in mean change between the two arms. Our results indicate that the low-fat dietary intervention was not associated with significant changes in hemostatic factors among postmenopausal women. |
| | |
Authors:
|
S N Rajpathak; X Xue; S Wassertheil-Smoller; L Van Horn; L Snetselaar; L W Martin; T E Rohan |
Publication Detail:
|
Type: Journal Article Date: 2010-09-29 |
Journal Detail:
|
Title: Nutrition, metabolism, and cardiovascular diseases : NMCD Volume: 22 ISSN: 1590-3729 ISO Abbreviation: Nutr Metab Cardiovasc Dis Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-03-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9111474 Medline TA: Nutr Metab Cardiovasc Dis Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 337-9 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: How many patients need statin treatment in a low-cardiovascular-risk country? Low-density lipoprotei...
Next Document: Mechanisms of tolerance and allergic sensitization in the airways and the lungs.