| Effect of local anaerobiosis on heart rate. | |
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MedLine Citation:
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PMID: 2096648 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The isolated leg of a rat was connected to the body only by nerve and bone and was perfused with hypoxic Tyrode solution. Heart rate increased when metabolic parameters (PCO2, pH and lactate) reached values similar to those observed at the beginning of exercise. When the muscle was additionally stimulated by electric stimuli a significant temporal correlation between lactate and heart or respiratory rate was found. Metabolic changes caused by hypoxia and muscular contraction, in particular lactic acid, appear to act as chemical stimuli for metabolic muscle receptors participating in the generation of circulatory and respiratory responses to physical exercise. |
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Authors:
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F Thimm |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Advances in experimental medicine and biology Volume: 277 ISSN: 0065-2598 ISO Abbreviation: Adv. Exp. Med. Biol. Publication Date: 1990 |
Date Detail:
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Created Date: 1991-07-15 Completed Date: 1991-07-15 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0121103 Medline TA: Adv Exp Med Biol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 459-66 Citation Subset: IM; S |
Affiliation:
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Physiologisches Institut, Universität Freiburg, F.R.G. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Afferent Pathways
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physiology Anaerobiosis / physiology Animals Anoxia / physiopathology* Heart Rate / physiology* Male Mechanoreceptors / physiology Muscle Contraction / physiology Muscles / innervation, metabolism Rats Rats, Inbred Strains Respiration / physiology |
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