Document Detail

Effect of lithium on reaction time--a study of diurnal variations.
MedLine Citation:
PMID:  6784147     Owner:  NLM     Status:  MEDLINE    
Continuous reaction time performance was measured in groups of normal controls, psychiatric controls and patients treated with lithium. The reaction times were slower for the patients treated with lithium compared to both groups of controls, but the performance was not impaired to the same degree as in patients with various forms of cerebral dysfunction. For all groups reaction times were slower in the morning than in the evening or at night. Slow reaction times at the first investigation in the groups of normal and psychiatric controls were positively correlated with larger variations in the 24 h course. However, this correlation could not be demonstrated for patients on lithium treatment, probably because these patients do not approach their limit of speed as often as other patients or controls.
P Elsass; E T Mellerup; O J Rafaelsen; A Theilgaard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychopharmacology     Volume:  72     ISSN:  0033-3158     ISO Abbreviation:  Psychopharmacology (Berl.)     Publication Date:  1981  
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7608025     Medline TA:  Psychopharmacology (Berl)     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  279-82     Citation Subset:  IM    
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MeSH Terms
Bipolar Disorder / drug therapy,  psychology
Circadian Rhythm / drug effects*
Lithium / pharmacology*,  therapeutic use
Middle Aged
Reaction Time / drug effects*
Reg. No./Substance:

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