Document Detail

Effect of lipoteichoic acid on thermotropic membrane properties.
MedLine Citation:
PMID:  9139903     Owner:  NLM     Status:  MEDLINE    
Lipoteichoic acid, diglucosyldiacylglycerol, and phosphatidylglycerol isolated from Staphylococcus aureus were embedded in dipalmitoylglycerophosphoglycerol vesicles, and their thermotropic influence on this matrix was studied by differential scanning calorimetry. The natural fatty acids of phosphatidylglycerol effected peak broadening and a decrease in molar heat capacity. These effects were more pronounced with the glycolipid, which also increased the main transition temperature. With the lipoteichoic acid mixtures, two broad main transition peaks were observed, possibly due to different levels of lipoteichoic acid in vesicles. Both peaks showed a further upshift in transition temperatures and a pronounced decrease in molar heat capacity. Since the diacylglycerol moieties of all three amphiphiles were practically identical, the differences in the thermotropic effects have to be ascribed to the different structures of the head groups. Diglucosyldiacylglycerol is proposed to exert an additional effect by hydrogen bonding the hydroxyls of the sugar rings to their phospholipid neighbors. The stronger effect of lipoteichoic acid points to dynamic interactions of the long hydrophilic chain with the vesicle surface, which stabilize the membrane structure.
T Gutberlet; J Frank; H Bradaczek; W Fischer
Related Documents :
5810083 - N-acylphosphatidylethanolamine, a phospholipid that is rapidly metabolized during the a...
9306733 - Characterization of bacterial phospholipids by electrospray ionization tandem mass spec...
573893 - The effect of aspartic acid on the intensity of physical dependence in morphine depende...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of bacteriology     Volume:  179     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-05-29     Completed Date:  1997-05-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2879-83     Citation Subset:  IM    
Institut für Kristallographie, Berlin, Federal Republic of Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Calorimetry, Differential Scanning
Fatty Acids / analysis
Lipopolysaccharides / chemistry*,  metabolism
Models, Molecular
Staphylococcus aureus / physiology
Teichoic Acids / chemistry*,  metabolism
Reg. No./Substance:
0/Fatty Acids; 0/Lipopolysaccharides; 0/Liposomes; 0/Phosphatidylglycerols; 0/Teichoic Acids; 4537-77-3/1,2-dipalmitoylphosphatidylglycerol; 56411-57-5/lipoteichoic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Unbalanced membrane phospholipid compositions affect transcriptional expression of certain regulator...
Next Document:  Lipopolysaccharide dependence of cyanophage sensitivity and aerobic nitrogen fixation in Anabaena sp...