Document Detail

Effect of a lipid-rich fraction from boiled coffee on serum cholesterol.
MedLine Citation:
PMID:  1971319     Owner:  NLM     Status:  MEDLINE    
Scandinavian-style boiled coffee, which raises serum cholesterol, was found to contain more lipid material than drip filter coffee, which does not. Ten volunteers consumed a lipid-enriched fraction from boiled coffee for six weeks: the supplement provided 77 g of water, 1.3 g of lipid, and 1.6 g of other solids per day. Serum cholesterol rose in every subject; the mean rise was 0.74 mmol/l after three weeks (range -0.09 to 1.48 mmol/l) and 1.06 SD 0.37 mmol/l or 23% after six weeks (range 0.48 to 1.52 mmol/l). The increase was mainly due to low-density-lipoprotein cholesterol, which rose by 29%, but very-low-density lipoprotein cholesterol was also raised, as evidenced by a 55% rise in triglycerides. High-density-lipoprotein cholesterol was unchanged. After supplementation had ended, lipid levels returned to baseline. Boiled coffee thus contains a lipid that powerfully raises serum cholesterol.
P L Zock; M B Katan; M P Merkus; M van Dusseldorp; J L Harryvan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  335     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-26     Completed Date:  1990-06-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1235-7     Citation Subset:  AIM; IM    
Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands.
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MeSH Terms
Cholesterol / blood*
Energy Intake
Evaluation Studies as Topic
Hot Temperature
Hypercholesterolemia / blood,  etiology
Lipids / administration & dosage*,  isolation & purification
Lipoproteins, LDL / blood
Time Factors
Reg. No./Substance:
0/Coffee; 0/Lipids; 0/Lipoproteins, LDL; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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