Document Detail

Effect of light-to-moderate alcohol consumption on age-associated arterial stiffening.
MedLine Citation:
PMID:  15820179     Owner:  NLM     Status:  MEDLINE    
Increased thickness and stiffness of large arteries may contribute to why aging is the most important risk for cardiovascular diseases. Arterial stiffness, intimal medial thickness, and alcohol intake were measured in 563 subjects. A U-shaped relation was found between alcohol intake and a stiffness index, with the lowest index in moderate drinkers, which may partially explain the relation between alcohol and cardiovascular disease.
Hidetaka Hougaku; Jerome L Fleg; Edward G Lakatta; Angelo Scuteri; Christopher J Earley; Samer Najjar; Saswata Deb; E Jeffrey Metter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  95     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-11     Completed Date:  2005-05-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1006-10     Citation Subset:  AIM; IM    
Clinical Research Branch, Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA.
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MeSH Terms
Aging / physiology
Alcohol Drinking / adverse effects*
Cardiovascular Diseases / etiology*
Carotid Arteries / anatomy & histology*,  pathology*
Longitudinal Studies
Middle Aged
Tunica Intima / anatomy & histology,  pathology
Vascular Resistance*

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