| Effect of lifetime intake of organically bound tritium and tritiated water on the oocytes of rats. | |
| | |
MedLine Citation:
|
PMID: 6709828 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Rats were continuously exposed to constant activity of tritium in drinking water (HTO group) or to tritium organically bound in food (T-food group) in the period from conception of F1 generation through maturity. Female offspring were killed at the age of 21 and 71 days and the oocytes in their ovaries were counted. Mean dose rates absorbed in the ovaries were for the HTO groups 7.25 +/- 0.37 and 14.73 +/- 0.79 mGy/day and for the T-food group 4.84 +/- 0.25 mGy/day. Reduction in the oocyte number in the ovaries of females exposed to tritiated food was bigger than in the ovaries of females exposed to tritiated water. The dependence of the survival of small oocytes on the dose rate and the corresponding total accumulated dose had an exponential character. The damaging effect of tritium was for the period from conception to 21 days of age bigger than from 21 to 71 days of age. Of all stages of oocyte development, the highest sensitivity to tritium irradiation was observed in small oocytes and oocytes with one complete layer of follicle cells. As a result, relative number of growing and large oocytes increased. |
| | |
Authors:
|
Z Pietrzak-Flis; M Wasilewska-Gomułka |
Related Documents
:
|
16585728 - The dxl calscan heel densitometer: evaluation and diagnostic thresholds. 2658958 - Irradiation and food processing. 9737428 - Mutagenicity and dna-damaging activity of decomposed products of food colours under uv ... 7828518 - Food irradiation. 12791158 - Masticatory performance: a protocol for standardized production of an artificial test f... 6485788 - From breastmilk to family food. infant feeding in three swedish communities. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Radiation and environmental biophysics Volume: 23 ISSN: 0301-634X ISO Abbreviation: Radiat Environ Biophys Publication Date: 1984 |
Date Detail:
|
Created Date: 1984-05-23 Completed Date: 1984-05-23 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0415677 Medline TA: Radiat Environ Biophys Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 61-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animal Feed Animals Cell Count Female Oocytes / radiation effects* Ovary / analysis Rats Rats, Inbred Strains Tritium / pharmacology*, urine Water |
| Chemical | |
Reg. No./Substance:
|
10028-17-8/Tritium; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Micronucleus formation in human melanoma xenografts following exposure to hyperthermia.
Next Document: Use of ascorbic acid in the 51Cr labelling of mouse fibrosarcoma cells.