Document Detail

Effect of lidocaine anesthesia on pattern of ventilation and pulmonary function tests.
MedLine Citation:
PMID:  482978     Owner:  NLM     Status:  MEDLINE    
The pattern of ventilation (consisting of tidal volume, frequency of breathing, minute ventilation, peak inspiratory flow rate, inspiratory time, mean inspiratory flow rate, and inspiatory time ratio) and pulmonary function tests (consisting of spirometry, lung volumes, and airway resistance) were measured in ten conscious, healthy subjects before and after anesthesia of the airways achieved by inhalation of lidocaine, to determine the role of the vagus nerves in the control of eupneic breathing. No significant change was found in the pattern of ventilation or in pulmonary function tests after airway anesthesia. These results are consistent with the observation that the vagus nerves do not play an important role in the control of eupneic breathing in humans.
B A Chaudhary; W A Speir
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  72     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1979-11-29     Completed Date:  1979-11-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1246-8, 1251     Citation Subset:  AIM; IM    
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MeSH Terms
Anesthesia, Inhalation*
Forced Expiratory Flow Rates
Lidocaine / pharmacology*
Lung Volume Measurements
Respiration / drug effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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