Document Detail


Effect of left atrial ablation on the quality of life in patients with atrial fibrillation.
MedLine Citation:
PMID:  18362429     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The current study aimed to investigate the effect of ablation therapy on the quality of life (QOL) in patients with atrial fibrillation (AF) by using a questionnaire specific for AF. METHODS AND RESULTS: A total of 86 patients (paroxysmal/chronic, 61/25) with drug-resistant AF undergoing extensive pulmonary vein isolation were recruited for the study. The QOL was quantitatively assessed by the Atrial Fibrillation Quality of Life Questionnaire at baseline, and 1, 3 and 6 months after the ablation. Sinus rhythm was maintained in 48/61 (79%) of the paroxysmal AF group, and 15/25 (60%) of those in the chronic AF group during 6 months after the initial ablation procedure. Among the patients without any AF recurrences, patients with chronic AF exhibited a substantial improvement in the QOL at 1 month after the procedure, and it remained unchanged until the end of the follow-up period. However, in the patients with paroxysmal AF, the QOL level gradually increased over a 6-month period. The patients with recurrent AF exhibited no improvement in the QOL. CONCLUSION: Although the clinical course of the QOL improvement was different, both paroxysmal and chronic AF patients gained better QOL to maintain sinus rhythm by means of catheter ablation.
Authors:
Shinsuke Miyazaki; Taishi Kuwahara; Atsushi Takahashi; Atsushi Kobori; Yoshihide Takahashi; Toshihiro Nozato; Hiroyuki Hikita; Akira Sato; Kazutaka Aonuma; Kenzo Hirao; Mitsuaki Isobe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  72     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-25     Completed Date:  2008-08-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  582-7     Citation Subset:  IM    
Affiliation:
Cardiovascular Center, Yokosuka Kyosai Hospital, 1-16 Yonegahamadori, Yokosuka 238-8558, Japan. mshinsuke@k3.dion.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Arrhythmia Agents / therapeutic use
Atrial Fibrillation / drug therapy,  physiopathology,  surgery*
Catheter Ablation* / methods
Chronic Disease
Female
Humans
Male
Middle Aged
Pulmonary Veins
Quality of Life
Questionnaires
Recurrence
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents

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