| Effect of lateral target motion on image registration accuracy in CT-guided helical tomotherapy: a phantom study. | |
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MedLine Citation:
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PMID: 20598016 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Optimisation of imaging modes for kilovoltage CT (kVCT) used for treatment planning and megavoltage CT (MVCT) image guidance used in ungated helical tomotherapy was investigated for laterally moving targets. Computed tomography images of the QUASAR Respiratory Motion Phantom were acquired without target motion and for lateral motion of the target, with 2-cm peak-to-peak amplitude and a period of 4 s. Reference kVCT images were obtained using a 16-slice CT scanner in standard fast helical CT mode, untagged average CT mode and various post-processed 4D-CT modes (0% phase, average and maximum intensity projection). Three sets of MVCT images with different inter-slice spacings of were obtained on a Hi-Art tomotherapy system with the phantom displaced by a known offset position. Eight radiation therapists performed co-registration of MVCT obtained with 2-, 4- and 6-mm slice spacing and kVCT studies independently for all 15 CT imaging combinations. In the investigated case, the untagged average kVCT and 4-mm slice spacing for the MVCT yielded more accurate registration in the transverse plane. The average residual uncertainty of this combination of imaging procedures was 0.61 +/- 0.16 mm in the longitudinal direction, 0.45 +/- 0.14 mm in the anterior-posterior direction and insignificant in the lateral direction. Manual registration of MVCT-kVCT study pairs is necessary to account for a target in significant lateral motion with respect to bony structures. |
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Authors:
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J Medwig; S Gaede; J J Battista; S Yartsev |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of medical imaging and radiation oncology Volume: 54 ISSN: 1754-9485 ISO Abbreviation: J Med Imaging Radiat Oncol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-05 Completed Date: 2010-12-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101469340 Medline TA: J Med Imaging Radiat Oncol Country: Australia |
Other Details:
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Languages: eng Pagination: 280-6 Citation Subset: IM |
Affiliation:
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London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Artifacts* Humans Motion Movement Phantoms, Imaging Radiographic Image Interpretation, Computer-Assisted / methods* Radiotherapy, Computer-Assisted / methods* Radiotherapy, Conformal / methods* Reproducibility of Results Respiratory Mechanics* Sensitivity and Specificity Tomography, Spiral Computed / instrumentation, methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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