Document Detail

Effect of late-onset sepsis on energy expenditure in extremely premature infants.
MedLine Citation:
PMID:  17413868     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to compare total energy expenditure (TEE) in extremely premature infants during and after an episode of sepsis. We hypothesized that TEE in the sepsis group (SEP) would be higher during the septic period and higher than an age-matched control group (CTL). We further hypothesized that the TEE of the SEP group during the recovery period would be similar to that of the CTL group. The doubly labeled water method was used to determine TEE in both groups. Infant characteristics were as follows: SEP group, n = 10, gestation = 26 +/- 1 wk, birth weight = 854 +/- 218 g; CTL group, n = 10, gestation = 26 +/- 1 wk, birth weight = 880 +/- 158 g. TEE of the SEP group during the septic period was significantly greater than during the recovery period (96 +/- 25 kcal/kg/d versus 55 +/- 17 kcal/kg/d) and significantly greater than the CTL group during the first study period (96 +/- 25 kcal/kg/d versus 67 +/- 12 kcal/kg/d). TEE in the SEP group during the recovery period was similar to the CTL group. These increases in TEE may contribute to impaired growth and need to be considered when providing nutritional support for extremely premature infants.
Ilana J Torine; Scott C Denne; Shirley Wright-Coltart; Catherine Leitch
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric research     Volume:  61     ISSN:  0031-3998     ISO Abbreviation:  Pediatr. Res.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-06-05     Completed Date:  2007-07-16     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  600-3     Citation Subset:  IM    
Department of Pediatrics, Section of Neonatal-Perinatal Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
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MeSH Terms
Body Water / chemistry,  metabolism
Deuterium / metabolism
Energy Metabolism*
Gestational Age
Infant, Newborn
Infant, Premature*
Infant, Premature, Diseases / physiopathology*
Oxygen Isotopes / metabolism
Sepsis / physiopathology*
Grant Support
Reg. No./Substance:
0/Oxygen Isotopes; 7782-39-0/Deuterium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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