Document Detail

Effect of L-arginine supplementation on blood pressure in pregnant women: a meta-analysis of placebo-controlled trials.
MedLine Citation:
PMID:  22957482     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: A meta-analysis of placebo-controlled trials was conducted to evaluate the effect of L-arginine supplementation on blood pressure (BP) in pregnancy.
METHODS: Trials were searched in PubMed, Embase, and Cochrane Library. A total of five trials were included in the meta-analysis.
RESULTS: L-arginine supplementation exhibited a mean decrease of 3.07 mmHg (p = 0.004) for diastolic blood pressure and a mean increase of 1.23 weeks (p = 0.002) for gestation age at delivery in pregnancy, but did not reduce systolic BP (p = 0.19) as compared to placebo.
CONCLUSION: L-arginine supplementation had a significant effect of lowering diastolic blood pressure and prolonging gestation age in pregnancy.
Qing Zhu; Xin Yue; Qing-Yin Tian; Gaowa Saren; Ming-Hui Wu; Yun Zhang; Tong-Tao Liu
Publication Detail:
Type:  Journal Article; Meta-Analysis     Date:  2012-09-07
Journal Detail:
Title:  Hypertension in pregnancy     Volume:  32     ISSN:  1525-6065     ISO Abbreviation:  Hypertens Pregnancy     Publication Date:  2013  
Date Detail:
Created Date:  2013-02-11     Completed Date:  2014-04-22     Revised Date:  2014-07-23    
Medline Journal Info:
Nlm Unique ID:  9421297     Medline TA:  Hypertens Pregnancy     Country:  England    
Other Details:
Languages:  eng     Pagination:  32-41     Citation Subset:  IM    
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MeSH Terms
Arginine / pharmacology,  therapeutic use*
Blood Pressure / drug effects*
Controlled Clinical Trials as Topic
Dietary Supplements
Gestational Age
Hypertension, Pregnancy-Induced / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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