| Effect of ketotifen on childhood asthma: a double-blind study. | |
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MedLine Citation:
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PMID: 2189866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ketotifen was administered orally, for 3 months, to 40 children aged 3-14 years with chronic extrinsic asthma of moderate severity in a double-blind placebo-controlled study. A significant clinical improvement with concomitant reduction of antiasthmatic drugs was found in the group receiving the active drug compared with the placebo group (p less than 0.05). The continued administration of ketotifen in an open study to a group of 21 children comprised of patients belonging to both groups (active-placebo) for a period of 15-18 months resulted in disappearance of symptoms in 10 children (47.6%) and moderate improvement in 7 (33.3%). |
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Authors:
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C Mylona-Karayanni; D Hadziargurou; G Liapi-Adamidou; I Anagnostakis; C Sinaniotis; F Saxoni-Papageorgiou |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: The Journal of asthma : official journal of the Association for the Care of Asthma Volume: 27 ISSN: 0277-0903 ISO Abbreviation: J Asthma Publication Date: 1990 |
Date Detail:
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Created Date: 1990-07-12 Completed Date: 1990-07-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8106454 Medline TA: J Asthma Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 87-93 Citation Subset: IM |
Affiliation:
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Second Department of Pediatrics, University of Athens, "P. & A. Kyriakou" Children's Hospital, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Asthma / drug therapy*, physiopathology Bronchodilator Agents / therapeutic use Child Child, Preschool Clinical Trials as Topic Double-Blind Method Female Forced Expiratory Volume / drug effects Humans Ketotifen / therapeutic use* Male |
| Chemical | |
Reg. No./Substance:
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0/Bronchodilator Agents; 34580-13-7/Ketotifen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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