| Effect of isovolemic hemodilution with dextran and albumin on thrombus formation in artificial vessel grafts inserted into the abdominal aorta of the rabbit. | |
| | |
MedLine Citation:
|
PMID: 7565028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of isovolemic hemodilution with dextran-70 and albumin on thrombus formation in artificial arterial grafts were investigated. A polytetrafluoroethylene graft (PTFE, length 13 mm, inner diameter 3 mm) was inserted into the abdominal aorta of rabbits. Three groups of animals were studied; 1) animals receiving isovolemic hemodilution with dextran-70 (10 ml/kg body weight), 2) animals receiving isovolemic hemodilution with albumin (10 ml/kg body weight), and 3) nonhemodiluted controls. The blood flow increased by about 70% and 60% after the hemodilution with dextran and albumin, respectively, and remained high in the hemodiluted animals, after insertion of the graft. After 2 days, the vessel graft was removed and weighed. The thrombus mass was separately weighed. The results suggest that isovolemic hemodilution with both albumin and dextran is associated with a marked increase in blood flow in the rabbit. Hemodilution with dextran also reduced the amount of thrombus formation on the inner wall of the graft. |
| | |
Authors:
|
L Frost-Arner; D Bergqvist |
Related Documents
:
|
3901378 - A low flow velocity predicts failure of femoropopliteal and femorotibial bypass grafts. 1298208 - Praxilene (naftidrofuryl oxalate) as an alternative for the augmentation of femoro-dist... 2110528 - The blood-brain barrier protects foreign antigens in the brain from immune attack. 18922708 - The haemodynamics of the distal arterial y-shaped autograft bypass-flap in a porcine ex... 12456708 - Fine-scale patterns of odor encounter by the antennules of mantis shrimp tracking turbu... 9416908 - Aqueous oxygen: a highly o2-supersaturated infusate for regional correction of hypoxemi... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Microsurgery Volume: 16 ISSN: 0738-1085 ISO Abbreviation: Microsurgery Publication Date: 1995 |
Date Detail:
|
Created Date: 1995-11-08 Completed Date: 1995-11-08 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8309230 Medline TA: Microsurgery Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 357-61 Citation Subset: IM |
Affiliation:
|
Department of Plastic and Reconstructive Surgery, Malmö General Hospital, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Albumins
/
pharmacology* Animals Aorta, Abdominal Blood Vessel Prosthesis* Dextrans / pharmacology* Female Fibrinolytic Agents / pharmacology* Hemodilution / methods* Male Rabbits Thrombosis / prevention & control* Vascular Patency |
| Chemical | |
Reg. No./Substance:
|
0/Albumins; 0/Fibrinolytic Agents; 9004-54-0/Dextrans |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?
Next Document: Diagnosis and treatment of myasthenia gravis. Experience 1974-1992