Document Detail

Effect of isosorbide dinitrate on enzymatically estimated infarction size and on clinical condition of the patients of acute myocardial infarction.
MedLine Citation:
PMID:  2391145     Owner:  NLM     Status:  MEDLINE    
With the aim of reducing myocardial infarction size, isosorbide dinitrate (ISDN) was tried in 27 patients of acute myocardial infarction (AMI). There was 11% reduction of infarction size, in the ISDN treated group, in comparison to that of non treated group, though the result was not statistically significant. But, many of the in-hospital complications were significantly less in the treated group. After a critical analysis of the result it was concluded that a statistically insignificant result, as regard reduction of infarction size in AMI, cannot always exclude the utility of a drug therapy in AMI.
D Mukherjee; S K Lodh; M Sengupta; A K Maity; A K Mondal; J C Ghose
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pathology & microbiology     Volume:  33     ISSN:  0377-4929     ISO Abbreviation:  Indian J Pathol Microbiol     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-10-02     Completed Date:  1990-10-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7605904     Medline TA:  Indian J Pathol Microbiol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  144-50     Citation Subset:  IM    
N.R.S. Medical College, Calcutta.
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MeSH Terms
Creatine Kinase / analysis
Isosorbide Dinitrate / therapeutic use*
Middle Aged
Myocardial Infarction / drug therapy*,  enzymology
Reg. No./Substance:
0/Isoenzymes; 87-33-2/Isosorbide Dinitrate; EC Kinase

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