| Effect of isoprenaline and nitroglycerine on pressure time indices and coronary graft blood flow in man. | |
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MedLine Citation:
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PMID: 820428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In five patients studied 1 to 3 d after coronary artery surgery isoprenaline and nitroglycerine have been used to alter the systolic (TTI) and diastolic (DPTI) pressure time indices. A close correlation with the predicted relationship between diastolic coronary graft flow and the DPTI/TTI ratio has been demonstrated during isoprenaline-induced tachycardia. Nitroglycerine reduced diastolic coronary graft resistance and increased the DPTI/TTI ratio, effects which are desirable for the relief of angina. |
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Authors:
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R Donaldson; A F Rickards; J E Wright; B T Williams; D Russell; R Balcon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiovascular research Volume: 10 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 1976 Mar |
Date Detail:
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Created Date: 1976-09-25 Completed Date: 1976-09-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 169-75 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Pressure / drug effects* Coronary Artery Bypass* Coronary Circulation / drug effects* Coronary Vessels / physiopathology Heart Rate / drug effects Humans Isoproterenol / pharmacology* Male Middle Aged Nitroglycerin / pharmacology* Time Factors Vascular Resistance / drug effects |
| Chemical | |
Reg. No./Substance:
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55-63-0/Nitroglycerin; 7683-59-2/Isoproterenol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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