Document Detail

Effect of isoflurane anesthesia on hemodynamics following the administration of an angiotensin-converting enzyme inhibitor in cats.
MedLine Citation:
PMID:  17827900     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to evaluate the hemodynamics of the anesthetic isoflurane in healthy cats given angiotensin-converting enzyme inhibitor (ACEI). The 7 healthy young cats and 3 old cats were received placebo or enalapril 0.5 mg/kg orally. The change in systolic arterial pressure from the baseline to 30 min postanesthesia in the ACEI group was significantly higher than in the placebo group (mean +/- SD: -39 +/- 13% vs. -17 +/- 12%, respectively). The present study indicated that general anesthesia may induce hypotension after the administration of an ACEI.
Yumi Ishikawa; Masami Uechi; Ryoukichi Ishikawa; Yoshito Wakao; Sei-ichi Higuchi
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  69     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-10     Completed Date:  2007-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  869-71     Citation Subset:  IM    
Ishikawa Animal Hospital, Yokosuka, Kanagawa, Japan.
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MeSH Terms
Anesthesia / adverse effects,  veterinary*
Anesthetics, Inhalation / adverse effects,  pharmacology*
Angiotensin-Converting Enzyme Inhibitors / administration & dosage*,  pharmacology*
Blood Pressure / drug effects*
Enalapril / administration & dosage,  pharmacology
Hypotension / chemically induced,  physiopathology
Isoflurane / adverse effects,  pharmacology*
Time Factors
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Angiotensin-Converting Enzyme Inhibitors; 26675-46-7/Isoflurane; 75847-73-3/Enalapril

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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