| Effect of ischemic mitral regurgitation on the ratio of early transmitral flow velocity to mitral annulus early diastolic velocity in patients with stable coronary artery disease. | |
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MedLine Citation:
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PMID: 16679081 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study evaluated the prevalence of ischemic mitral regurgitation (MR) in a large population of patients with documented coronary artery disease who had been referred for echocardiography and assessed whether ischemic MR is an independent determinant of echocardiographically estimated left ventricular (LV) filling pressures. We studied 849 consecutive patients with coronary artery disease (67 +/- 10 years; 76% men) without organic valvular disease. Ischemic MR was semiquantitatively graded as absent or trace or grades 1 to 3/4 by assessment of the color flow jet in relation to the left atrium in multiple orthogonal views. The ratio of early transmitral flow velocity to mitral annulus early diastolic velocity was determined to estimate LV filling pressures. Ischemic MR was absent in 25% of patients and 28% had grade > or = 2 ischemic MR. Only 18% of patients with preserved LV function had a significant ischemic MR, but up to 66% of patients with poor LV function had grade > or = 2 MR. The ratio of early transmitral flow velocity to mitral annulus early diastolic velocity was independently predicted by age, gender, LV ejection fraction, and ischemic MR severity. Even mild ischemic MR was associated with an increase in this noninvasive marker of LV filling pressures. |
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Authors:
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Nico R Van de Veire; Johan De Sutter |
Publication Detail:
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Type: Journal Article Date: 2006-03-24 |
Journal Detail:
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Title: The American journal of cardiology Volume: 97 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-05-08 Completed Date: 2006-06-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1449-51 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Ghent University Hospital, Ghent, Belgium. nico.vandeveire@ugent.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Belgium / epidemiology Blood Flow Velocity / physiology* Coronary Artery Disease / physiopathology*, ultrasonography Diastole / physiology* Echocardiography, Doppler Female Humans Linear Models Male Middle Aged Mitral Valve Insufficiency / epidemiology, physiopathology*, ultrasonography Prevalence Retrospective Studies Sensitivity and Specificity Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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