Document Detail

Effect of iron fortification of nursery complementary food on iron status of infants in the DPRKorea.
MedLine Citation:
PMID:  18586646     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to determine the iron status of infants who consumed porridge cooked in water with added ferrous sulphate. A total of 234 infants, aged 6-12 months, were recruited from 36 nurseries in the Democratic Peoples Republic of Korea (DPRK North Korea) and randomly divided into iron (Fe) and placebo groups. At baseline, almost half the children had Hb<110 g/L and no significant differences between the two groups were found with regard to hemoglobin concentration and anemia prevalence. The Fe group received rice porridge fortified with 10 mg of iron (as ferrous sulfate) per day, added to the water in which the rice was cooked and the placebo group non-fortified cereal for 6 months. After which, the hemoglobin (Hb), serum ferritin (SF) and packed cell volume (PCV) were measured and it was found that the proportion of children with anemia (Hb<110 g/L) was lower (24.3% v 48.1% p<0.01), the Hb levels (117.6 g/L v 109.8 g/L p<0.001) and serum ferritin were higher (40.7 v 26.8 mcg/L p<0.001); and iron deficiency anemia (Hb<110 g/L, SF<12 mcg/L) was lower in the Fe group (3% v 22% p<0.001) when compared to the placebo group. Ferrous sulphate, added to the water in which rice was cooked, lowered the prevalence of iron deficiency anemia of infants in the DPRK with no adverse reactions. This simple fortification would be suitable as a nationwide program in the DPRK and other countries with large infant nurseries.
HuiYong Rim; SuHuan Kim; ByongChel Sim; HaeYong Gang; HoYong Kim; YongRan Kim; RakChel Kim; MunHui Yang; SangPil Kim
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Asia Pacific journal of clinical nutrition     Volume:  17     ISSN:  0964-7058     ISO Abbreviation:  Asia Pac J Clin Nutr     Publication Date:  2008  
Date Detail:
Created Date:  2008-06-30     Completed Date:  2009-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440304     Medline TA:  Asia Pac J Clin Nutr     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  264-9     Citation Subset:  IM    
Institute of Child Nutrition, Academy of Medical Sciences Saesalim dong, Tongdaewon District, Pyongyang, DPR Korea.
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MeSH Terms
Anemia, Iron-Deficiency / blood,  drug therapy*,  epidemiology
Cereals / chemistry
Food, Fortified*
Hemoglobins / drug effects
Infant Nutritional Physiological Phenomena / drug effects*,  physiology
Iron / blood,  metabolism
Iron, Dietary / administration & dosage*,  adverse effects
Nutritional Status*
Treatment Outcome
Reg. No./Substance:
0/Hemoglobins; 0/Iron, Dietary; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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