| Effect of intraoperative fluid administration and colloid osmotic pressure on the formation of intestinal edema during gastrointestinal surgery. | |
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MedLine Citation:
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PMID: 1702977 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of intraoperative changes in plasma colloid osmotic pressure (COP) on the formation of intestinal edema were studied in patients during modified Whipple's operation (hemipancreato-duodenectomy). Eighteen patients (ASA physical status I or II) were randomly assigned to one of three groups. They received either lactated Ringer's (RL group, n = 6), 10% hydroxyethyl starch (HES group, n = 6), or 20% human albumin (HA group, n = 6) as a volume replacement solution, which was given to maintain central venous pressure (CVP) at the preoperative level. Jejunal specimens were obtained after the first transsection of the jejunum and prior to the jejuno-jejunostomy. Their water fraction (g H2O/g tissue dry weight) was measured gravimetrically. COP was determined prior to induction of anesthesia and upon removal of the second jejunal sample. In the RL group, 3,850 +/- 584 ml (data are means +/- SEM) of volume replacement solution were infused from induction of anesthesia to removal of the second jejunal sample. In the HES group, 1,358 +/- 45 ml were infused, and in the HA group, 463 +/- 49 ml were infused. During this time, COP decreased from 20.3 +/- 0.5 mmHg to 14.1 +/- 0.6 mmHg in the RL group, remained at 22.0 +/- 0.9 mmHg in the HES group, and increased from 20.7 +/- 0.9 mmHg to 28.1 +/- 0.9 mmHg in the HA group.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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T Prien; N Backhaus; F Pelster; W Pircher; H Bünte; P Lawin |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of clinical anesthesia Volume: 2 ISSN: 0952-8180 ISO Abbreviation: J Clin Anesth Publication Date: 1990 Sep-Oct |
Date Detail:
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Created Date: 1991-02-25 Completed Date: 1991-02-25 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8812166 Medline TA: J Clin Anesth Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 317-23 Citation Subset: IM |
Affiliation:
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Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Westfälische Wilhelms-Universität Münster, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Albumins
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administration & dosage Blood Physiological Phenomena* Blood Proteins / analysis Blood Transfusion Central Venous Pressure Duodenum / surgery* Edema / etiology* Female Fluid Therapy* Hetastarch / administration & dosage Humans Intestinal Diseases / etiology* Intraoperative Care* Isotonic Solutions / administration & dosage Jejunostomy Jejunum / pathology Male Middle Aged Osmotic Pressure Pancreatectomy / methods* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Albumins; 0/Blood Proteins; 0/Isotonic Solutions; 8022-63-7/Ringer's lactate; 9005-27-0/Hetastarch |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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