Document Detail

Effect of intramuscular administration of dexamethasone on the duration of labor.
MedLine Citation:
PMID:  18534594     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effect of dexamethasone administration on labor duration. METHOD: In this controlled trial 122 nulliparous women with a full-term pregnancy and a Bishop score of 7 or greater were randomly assigned to receive a single 8-mg dose of dexamethasone or placebo 6 hours before initiation of labor induction. RESULTS: The interval between initiation of labor induction and beginning of the active phase of labor was shorter in the dexamethasone than in the control group (3.09+/-1.5 hours vs. 4.21+/-1.8 hours; P=0.001). The duration of the second stage of labor was also shorter in the dexamethasone group (22.23+/-16.09 minutes vs. 29.01+/-15.32 minutes; P=0.014). CONCLUSION: The administration of dexamethasone was found to shorten labor duration.
Maryam Kashanian; Farideh Dadkhah; Fattaneh Mokhtari
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-06-04
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  102     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-22     Completed Date:  2008-11-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran.
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MeSH Terms
Dexamethasone / administration & dosage*,  adverse effects
Double-Blind Method
Injections, Intramuscular
Labor, Obstetric / drug effects*
Oxytocics / administration & dosage*,  adverse effects
Time Factors
Reg. No./Substance:
0/Oxytocics; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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