Document Detail

Effect of intra-operative pressure support vs pressure controlled ventilation on oxygenation and lung function in moderately obese adults.
MedLine Citation:
PMID:  19958342     Owner:  NLM     Status:  MEDLINE    
Obesity impairs peri-operative lung function. To evaluate the impact of pressure support ventilation vs pressure controlled ventilation in moderately obese adults upon early postoperative lung function, we randomly assigned 68 moderately obese patients (body mass index 25-35 kg x m(-2)) undergoing minor surgery to receive intra-operative ventilation either with pressure support or pressure controlled ventilation. We performed intra-operative blood gas analysis and measured pulse oximetry saturation, spirometry values at pre-operative assessment (baseline) and at 10 min, 30 min, 2 h and 24 h after extubation. The intra-operative oxygenation index (arterial partial pressure of oxygen/fraction of inspired oxygen) in the pressure support ventilation group was significantly improved over time (p < 0.0001). Postoperatively, the pressure support ventilation group also had better lung function and oxygenation values than did the pressure controlled ventilation group (p < 0.005). We conclude that pressure support ventilation better maintains lung function than pressure controlled ventilation in moderately overweight patients scheduled for minor surgery.
M Zoremba; G Kalmus; F Dette; C Kuhn; H Wulf
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-12-03
Journal Detail:
Title:  Anaesthesia     Volume:  65     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-04-20     Completed Date:  2010-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  124-9     Citation Subset:  AIM; IM    
Department of Anesthesia and Intensive Care Medicine, University of Marburg, Marburg, Germany.
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MeSH Terms
Anesthesia, General
Body Mass Index
Intraoperative Care / methods*
Lung / physiopathology*
Middle Aged
Obesity / physiopathology*
Oxygen / blood*
Partial Pressure
Positive-Pressure Respiration
Postoperative Period
Respiration, Artificial / methods*
Surgical Procedures, Minor
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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