Document Detail


Effect of interval between transcatheter hepatic arterial embolization and radiofrequency ablation on ablated lesion size in a swine model.
MedLine Citation:
PMID:  21956371     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: The aim of the study was to clarify the effect of the interval between transcatheter hepatic arterial embolization (TAE) with Lipiodol plus gelatin sponge particles and radiofrequency (RF) ablation on the extent of ablation.
MATERIALS AND METHODS: Eight healthy swine were divided into four groups: RF ablation (ablation only), RF ablation immediately after TAE (immediate ablation), RF ablation 3 days after TAE (3-day ablation), and RF ablation 6 days after TAE (6-day ablation). Five ablated lesions were created in each swine (10 per group). A 2-cm expandable LeVeen needle electrode was used for RF ablation. Ablated lesions are composed of an outer reddish zone and an inner whitish zone.
RESULTS: The average longest length of the major, intermediate, and minor axes and the volume in the immediate ablation, 3-day ablation, and 6-day ablation groups were significant longer and greater (1.52 and 1.52, 1.46 and 1.50, and 1.37 and 1.35 times greater in the red zone and the whitish area, respectively) than those in the ablation-only group (P < 0.05/3). Accumulation of Lipiodol was still noted in the hepatic sinusoids in the 3-day and 6-day ablation groups.
CONCLUSION: RF ablation delayed to 6 days following TAE produced larger ablation volumes than did RF ablation alone.
Authors:
Cao Guang; Nobuyuki Kawai; Morio Sato; Isao Takasaka; Hiroki Minamiguchi; Shinya Sahara; Kouhei Nakata; Tetsuo Sonomura; Shintaro Shirai; Ichiro Mori; Renjie Yang
Publication Detail:
Type:  Journal Article     Date:  2011-09-29
Journal Detail:
Title:  Japanese journal of radiology     Volume:  29     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-09-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  649-55     Citation Subset:  IM    
Affiliation:
Department of Radiology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8510, Japan.
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