Document Detail

Effect of inspired CO(2) on the ventilatory response to high intensity exercise.
MedLine Citation:
PMID:  22198479     Owner:  NLM     Status:  Publisher    
We tested the hypothesis that preventing the poikilocapnic response to high intensity exercise would increase the ventilatory response to exercise. We measured ventilatory variables in 10 healthy men during incremental cycling with and without inspired CO(2) (randomised order). Inspired CO(2) elevated resting ventilation (V˙(E)), tidal volume (V(T)), [Formula: see text] and [Formula: see text] by 5±5L/min, 0.3±0.2L, 6±3mmHg and 11±7mmHg, respectively (P<0.05); resting breathing frequency (f), expired CO(2) [Formula: see text] and O(2) consumption [Formula: see text] remained similar (P>0.05). During high intensity exercise, inspired CO(2) elevated [Formula: see text] by 7±2, 10±4 and 11±4mmHg at 80%, 90% and 100% [Formula: see text] , respectively (P<0.01), while [Formula: see text] remained unchanged (P>0.05). During high intensity exercise, inspired CO(2) elevated VT by 0.2±0.3L at 80%, 90% and 100% [Formula: see text] , respectively (P<0.05), while no differences were observed in V˙(E), f, [Formula: see text] , or power output (P>0.05). These data suggest a progressively diminishing role of CO(2) chemoreception in the control of ventilation during maximal incremental exercise.
Jui-Lin Fan; Christian Leiggener; Florian Rey; Bengt Kayser
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-16
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  -     ISSN:  1878-1519     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
Institute of Movement Sciences and Sports Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland; Lemanic Doctoral School of Neuroscience, University of Geneva, Geneva, Switzerland.
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