Document Detail

Effect of inositol hexaphosphate on retention of zinc and calcium from the human colon.
MedLine Citation:
PMID:  2269248     Owner:  NLM     Status:  MEDLINE    
Colonic retention of zinc and calcium was studied after installation during colonoscopy in 11 patients of a solution of 30 mumol zinc, 6.4 mmol calcium and 500 mumol inositol hexaphosphate (phytic acid) labelled with 65Zn and 47Ca. Whole-body retention of the radionuclide at day 13 was 1.0 +/- 1.0 per cent (mean +/- s.d.) for zinc and 4.0 +/- 2.9 per cent for calcium. The retention of zinc but not of calcium was lower than observed earlier under similar conditions from a solution not containing phytic acid and indicates formation of an indigestible complex between phytic acid and zinc. Addition of amino acids to the solution in 3 subjects did not seem to affect the retention of zinc and calcium.
B Sandström; A Cederblad; B Stenquist; H Andersson
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  44     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-02-21     Completed Date:  1991-02-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  705-8     Citation Subset:  IM    
Research Department of Human Nutrition, Copenhagen, Denmark.
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MeSH Terms
Amino Acids / pharmacology
Calcium / metabolism*
Calcium Radioisotopes / diagnostic use
Colon / metabolism*
Depression, Chemical
Middle Aged
Phytic Acid / pharmacology*
Zinc / metabolism*
Zinc Radioisotopes / diagnostic use
Reg. No./Substance:
0/Amino Acids; 0/Calcium Radioisotopes; 0/Zinc Radioisotopes; 7440-66-6/Zinc; 7440-70-2/Calcium; 83-86-3/Phytic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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