Document Detail

Effect of inhaled salbutamol on coronary circulation in humans.
MedLine Citation:
PMID:  16891006     Owner:  NLM     Status:  MEDLINE    
In 12 patients we assessed the effect of inhaled salbutamol on the coronary circulation. According to our results, large doses of salbutamol increase coronary flow, but not in proportion to the needs of the myocardium (as documented by the increase in coronary oxygen extraction), and decrease coronary flow reserve. These effects may have deleterious consequences in patients with coronary artery disease, causing or worsening myocardial ischemia.
George E Kochiadakis; Michael I Hamilos; Emmanuel I Skalidis; Nikolaos E Igoumenidis; Sophia E Schiza; Panos E Vardas
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Publication Detail:
Type:  Letter     Date:  2006-08-07
Journal Detail:
Title:  International journal of cardiology     Volume:  117     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  408-10     Citation Subset:  IM    
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MeSH Terms
Administration, Inhalation
Adrenergic beta-Agonists / administration & dosage*
Albuterol / administration & dosage*
Coronary Circulation / drug effects*
Middle Aged
Reg. No./Substance:
0/Adrenergic beta-Agonists; 18559-94-9/Albuterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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