Document Detail

Effect of inflow on computational fluid dynamic simulation of cerebral bifurcation aneurysms.
MedLine Citation:
PMID:  22254487     Owner:  NLM     Status:  MEDLINE    
Morphological characteristics associated with cerebral aneurysm formation can be used to assess aneurysm rupture. This study investigated hemodynamic effects resulting from change in the parent artery diameter of bifurcation type aneurysm. Computational fluid dynamic (CFD) analysis was performed on middle cerebral artery (MCA) models with various parent artery diameters. Calculations were performed with steady flow rate (125 ± 12.5 ml/min) at the parent artery inlet. Energy loss (EL) was calculated from pressure and kinetic energy obtained from flow velocity. The results indicate that the high wall shear stress (WSS) and EL occurs in model with the smallest parent vessel compared to the other models for all three inflows. Results also showed that 10% variation of inflow results in average of 23 ± 2.9% changes in WSS and 25.5 ± 0.5% changes in energy loss. These results demonstrated that for CFD analysis of MCA bifurcation type aneurysm, upstream parent vessel and inflow evaluation for individual patient is essential.
A Farnoush; Y Qian; A Avolio
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-06-07     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1025-8     Citation Subset:  IM    
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MeSH Terms
Aneurysm, Ruptured / physiopathology*
Blood Flow Velocity
Blood Pressure
Cerebral Arteries / physiopathology*
Cerebrovascular Circulation*
Intracranial Aneurysm / physiopathology*
Models, Cardiovascular*
Models, Neurological*
Shear Strength

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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