| Effect of induction dose, lactation stage and body condition on tiletamine-zolazepam anaesthesia in adult female grey seals (Halichoerus grypus) under field conditions. | |
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MedLine Citation:
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PMID: 21508066 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tiletamine-zolazepam (TZ) was used at a mean (sd) dose of 1.18 (0.15) mg/kg administered intramuscularly to anaesthetise adult female grey seals (Halichoerus grypus) under field conditions at three different stages during their lactation period. A significant correlation was observed between the induction dose and time to induction (r=-0.582, P=0.011). Stage of lactation had a significant effect on condition index (CI), calculated as axial girth divided by length (P<0.001), and time to induction (P=0.009). No effect of CI on induction or recovery time was demonstrated. Respiratory rate decreased during induction and increased significantly (P<0.001) during surgical biopsy of blubber. Recovery occurred after 32.5 (11.9) minutes. Minor complications (tremor, vocalisation and mild dyspnoea) were observed in a small number of cases, none of which required treatment. |
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Authors:
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S D Langton; S E Moss; P P Pomeroy; K E Borer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2011-04-20 |
Journal Detail:
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Title: The Veterinary record Volume: 168 ISSN: 2042-7670 ISO Abbreviation: Vet. Rec. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-29 Completed Date: 2011-07-28 Revised Date: 2012-05-10 |
Medline Journal Info:
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Nlm Unique ID: 0031164 Medline TA: Vet Rec Country: England |
Other Details:
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Languages: eng Pagination: 457 Citation Subset: IM |
Affiliation:
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Royal Veterinary College, North Mymms, Hertfordshire, UK. s.langton@vet.gla.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia Recovery Period Anesthesia, Intravenous / veterinary* Anesthetics / administration & dosage* Animal Welfare Animals Animals, Wild Body Constitution / physiology Dose-Response Relationship, Drug Drug Combinations Female Infusions, Intravenous / veterinary Lactation / physiology* Respiratory Rate / drug effects Seals, Earless / physiology* Tiletamine / administration & dosage* Zolazepam / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics; 0/Drug Combinations; 0/tiletamine, zolazepam drug combination; 14176-49-9/Tiletamine; 31352-82-6/Zolazepam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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