| Effect of an indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus. | |
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MedLine Citation:
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PMID: 15742354 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Combating heart disease is one of the challenging problems of biomedical science today. Towards this goal an indigenous preparation 'Trikatu' (a herbal combination containing Piper longum (fruit), Piper nigrum (fruit) and Zingiber officinale (rhizome) dry powder) was fed to normal and cholesterol fed male Rattus norvegicus to ascertain its efficacy as a hypolipidaemic agent. Its effects on body weight, blood and tissue (aortic, cardiac and hepatic) lipids--total, free and esterified cholesterol, low density lipoprotein(LDL) and high density lipoprotein(HDL) cholesterol, triglycerides and phospholipids--and the atherogenic index were measured. It was found that 'Trikatu' by virtue of its ability to reduce triglycerides and LDL cholesterol and to increase HDL cholesterol can reduce the risk of hyperlipidaemia and atherosclerosis. Hence 'Trikatu' can be used as a potent hypolipidaemic agent and it can reduce the atherosclerosis associated with a high fat diet. |
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Authors:
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Valsala Sivakumar; S Sivakumar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 18 ISSN: 0951-418X ISO Abbreviation: Phytother Res Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2005-03-08 Completed Date: 2005-05-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 976-81 Citation Subset: IM |
Copyright Information:
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2004 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Zoology, Annamalai University, Annamalai nagar, 608002 Tamil Nadu, India. drvalsacdm@yahoo.co.in |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antilipemic Agents / administration & dosage, pharmacology*, therapeutic use Cholesterol / blood Cholesterol, HDL / blood Cholesterol, LDL / blood Diet, Atherogenic Dietary Supplements Fruit Ginger Male Obesity / blood, diet therapy* Phospholipids / metabolism Phytotherapy* Piper Plants, Medicinal* Rats Rhizome Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Phospholipids; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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