Document Detail

Effect of increased plasma osmolality on cold-induced thirst attenuation.
MedLine Citation:
PMID:  18758804     Owner:  NLM     Status:  MEDLINE    
The effects of elevating plasma osmolality (P (osm)) on thirst ratings was studied in eight dehydrated males during exposure to 4 degrees C. On two occasions, subjects were dehydrated (DH; 3-4% body mass) via 90 min exercise-heat exposure and overnight fluid restriction (day 1). On a third occasion, subjects were exposed to heat but were given fluid (EU). On day 2, subjects consumed NaCl (NaCl; 0.1 g NaCl kg(-1) body mass in 500 ml H(2)O; DH only) or Placebo (P; 500 ml H(2)O; DH and EU). Subjects stood for 30 min at 24 degrees C and for 45 min at 4 degrees C (75 min post-dose). P (osm) was elevated (P < 0.05) 30 and 75 min after NaCl administration in DH + NaCl versus DH + P and EU + P treatments. Thirst ratings remained elevated (P < 0.05) in the DH + NaCl treatment 30 min after dosing and 45 min at 4 degrees C versus DH + P and EU + P. Attenuation of thirst when dehydrated in the cold can be over-ridden by increasing P (osm).
Robert William Kenefick; A St Pierre; N A Riel; S N Cheuvront; J W Castellani
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Publication Detail:
Type:  Journal Article     Date:  2008-08-29
Journal Detail:
Title:  European journal of applied physiology     Volume:  104     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-05     Completed Date:  2009-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1013-9     Citation Subset:  IM    
Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas Street, Natick, MA, 01760, USA,
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MeSH Terms
Adaptation, Physiological / physiology
Blood Physiological Phenomena*
Blood Viscosity / physiology
Cold Temperature*
Dehydration / physiopathology,  therapy
Fluid Therapy
Osmolar Concentration
Plasma / physiology*
Plasma Volume / physiology*
Thirst / physiology*
Water-Electrolyte Balance / physiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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