Document Detail


Effect of increased knee joint pressure on oxygen tension and blood flow in subchondral bone.
MedLine Citation:
PMID:  6475543     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have investigated the influence of acute changes in the knee joint pressure of rabbits on the oxygen tension and the regional blood flow in the subchondral bone. The intra-articular pressure was increased by infusion of a sodium chloride solution into the joint cavity, and the associated change in the subchondral oxygen tension was measured by mass spectrometry. The mass spectrometer was also used to detect, qualitatively, changes in the regional blood flow. When the joint pressure was increased from the habitual level to 75 mmHg, the average subchondral oxygen tension was reduced from about 39 to about 30 mmHg and, at the same time, the regional blood flow was reduced significantly.
Authors:
J Grønlund; H Kofoed; E Svalastoga
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta physiologica Scandinavica     Volume:  121     ISSN:  0001-6772     ISO Abbreviation:  Acta Physiol. Scand.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-10-17     Completed Date:  1984-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370362     Medline TA:  Acta Physiol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  127-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone and Bones / blood supply*
Knee Joint / physiology*
Mass Spectrometry
Oxygen
Partial Pressure
Pressure
Rabbits
Regional Blood Flow
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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