Document Detail

Effect of increased intracranial pressure on arterial peripheral and cerebral blood pressure.
MedLine Citation:
PMID:  9342936     Owner:  NLM     Status:  MEDLINE    
The effect of increased intracranial pressure (ICP) on arterial peripheral (PBP) and cerebral blood pressure (CBP) was studied in 16 rabbits (New Zealand White). Changes of arterial blood pressure in peripheral and cerebral blood circulation were caused by a temporary (3 min) ICP increase. A raised ICP was obtained by infusing into the left lateral brain ventricle artificial cerebrospinal fluid at a pressure equal to 50, 100, and 150% of the initial CBP value. The experiments carried out showed that on reaching the initial CBP value, increased ICP induced Cushing response. The magnitude and duration of this reaction changed with increasing ICP, the intensity of the changes depending on the brain region in which the ICP increase was initiated.
M Dmowska; R Schoenborn; E Modrzejewski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia biologica     Volume:  44     ISSN:  0015-5497     ISO Abbreviation:  Folia Biol. (Krakow)     Publication Date:  1996  
Date Detail:
Created Date:  1997-12-08     Completed Date:  1997-12-08     Revised Date:  2006-12-14    
Medline Journal Info:
Nlm Unique ID:  2984758R     Medline TA:  Folia Biol (Krakow)     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  117-22     Citation Subset:  IM    
Department of Animal Physiology, M. Curie-Skłodowska University, Lublin, Poland.
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MeSH Terms
Blood Pressure*
Cerebral Ventricles / physiology
Cerebrospinal Fluid / physiology
Intracranial Pressure*

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