Document Detail


Effect of increased bromide intake on iodine excretion in rats.
MedLine Citation:
PMID:  9096849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The time course of iodine excretion in adult male rats substantially differs from bromine excretion. Bromine is excreted at a single rate, whereas iodine evinces two excretion rates. Even a strong increase in bromide intake in experimental animals failed to affect the rate of iodine excretion but it lowered the fraction of iodine accumulated in the thyroid gland by 20% probably by affecting the transport of iodide into the thyroid gland.
Authors:
M Vobecký; A Babický; J Lener
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biological trace element research     Volume:  55     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-06-10     Completed Date:  1997-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-9     Citation Subset:  IM    
Affiliation:
Academy of Sciences of Czech Republic, Institute of Analytical Chemistry, Praha, Czech Republic.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bromides / administration & dosage,  pharmacology*
Bromine / metabolism*
Half-Life
Injections, Subcutaneous
Iodine / metabolism*
Iodine Radioisotopes
Isotope Labeling
Male
Rats
Rats, Wistar
Thyroid Gland / metabolism*,  radionuclide imaging
Whole-Body Counting
Chemical
Reg. No./Substance:
0/Bromides; 0/Iodine Radioisotopes; 7553-56-2/Iodine; 7726-95-6/Bromine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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