| Effect of impact exercise on bone metabolism. | |
| | |
MedLine Citation:
|
PMID: 19262975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
SUMMARY: Regular impact exercise in premenopausal women caused positive osteogenic effects associated to low basal serum parathormone (PTH) but had no effects on bone turnover markers PINP or TRACP5b. The low serum basal PTH levels during impact exercise may be a sign of increased incorporation of calcium to bone. INTRODUCTION: This study aimed to determine the long-term effects of high-impact exercise on bone turnover and calciotropic hormones. METHODS: We performed a 12-month population-based, randomized, controlled exercise trial in 120 women (age 35-40 years) randomly assigned to an exercise group (EG; n = 60) or a control group (CG; n = 60). The exercise regimen consisted of supervised high-impact exercises three times per week. Daily impact loading was assessed by using an accelerometer. Bone turnover markers and calciotropic hormones were analyzed at 0, 6, and 12 months. RESULTS: Twelve months of impact exercise did not reveal any treatment effects in bone turnover markers PINP or TRAPC5b, whereas serum basal PTH decreased significantly more in the EG than in the CG (-11.2 vs. -2.2 pg/mL; p = 0.03). The change in PTH was dose dependent and most clearly seen in subjects with 96 to 130 daily impacts at 2.5 to 5.3 g (e.g., running or jumping). CONCLUSIONS: Regular impact exercise does not cause persistent alterations in bone turnover emphasizing necessity of continuous training to achieve bone benefits. Impact exercise training lowers the serum basal PTH levels and possibly enables greater difference between the basal PTH and transient exercise-induced PTH peaks leading to osteogenic effects. |
| | |
Authors:
|
A Vainionpää; R Korpelainen; H K Väänänen; J Haapalahti; T Jämsä; J Leppäluoto |
Related Documents
:
|
14672435 - Evaluation of serum concentrations of biochemical markers of bone metabolism and insuli... 16414925 - Carbon content variation in boles of mature sugar maple and giant sequoia. 6694935 - Understanding osteoporosis. cornerstone of prevention and treatment. 10441915 - Exercise and female adolescents: effects on the reproductive and skeletal systems. 17172795 - The effect of passive foot flexion on blood circulation in sports and clinical medicine. 11275945 - Decreased pituitary sensitivity to glucocorticoids in endurance-trained men. |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2009-03-05 |
Journal Detail:
|
Title: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA Volume: 20 ISSN: 1433-2965 ISO Abbreviation: Osteoporos Int Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-09-04 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9100105 Medline TA: Osteoporos Int Country: England |
Other Details:
|
Languages: eng Pagination: 1725-33 Citation Subset: IM |
Affiliation:
|
Department of Medical Technology, Institute of Biomedicine, University of Oulu, Oulu, Finland. aki.vainionpaa@fimnet.fi |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acid Phosphatase
/
blood Adult Biological Markers / blood Bone Density / physiology Bone and Bones / metabolism* Exercise Therapy / methods* Female Femur / physiology Humans Isoenzymes / blood Motor Activity / physiology Parathyroid Hormone / blood Peptide Fragments / blood Premenopause / metabolism, physiology Procollagen / blood Tibia / physiology Weight-Bearing / physiology |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Isoenzymes; 0/Parathyroid Hormone; 0/Peptide Fragments; 0/Procollagen; 0/procollagen Type I N-terminal peptide; EC 3.1.3.-/tartrate-resistant acid phosphatase; EC 3.1.3.2/Acid Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of PTH treatment on tibial bone of ovariectomized rats assessed by in vivo micro-CT.
Next Document: Rapid and accurate determination of relative infarct size in humans using contrast-enhanced magnetic...